zzam, E., Khlosy, H., Abouarab, M. (2020). The Efficacy of Autologous Nanofat Injection in the Treatment of Infraorbital Dark Colouration. The Egyptian Journal of Plastic and Reconstructive Surgery, 43(3), 445-452. doi: 10.21608/ejprs.2020.68188
Ehab zzam; Hassan M Khlosy; Mohamed H Abouarab. "The Efficacy of Autologous Nanofat Injection in the Treatment of Infraorbital Dark Colouration". The Egyptian Journal of Plastic and Reconstructive Surgery, 43, 3, 2020, 445-452. doi: 10.21608/ejprs.2020.68188
zzam, E., Khlosy, H., Abouarab, M. (2020). 'The Efficacy of Autologous Nanofat Injection in the Treatment of Infraorbital Dark Colouration', The Egyptian Journal of Plastic and Reconstructive Surgery, 43(3), pp. 445-452. doi: 10.21608/ejprs.2020.68188
zzam, E., Khlosy, H., Abouarab, M. The Efficacy of Autologous Nanofat Injection in the Treatment of Infraorbital Dark Colouration. The Egyptian Journal of Plastic and Reconstructive Surgery, 2020; 43(3): 445-452. doi: 10.21608/ejprs.2020.68188
The Efficacy of Autologous Nanofat Injection in the Treatment of Infraorbital Dark Colouration
The Department of Plastic Surgery, Faculty of Medicine, Alexandria University, Egypt
Abstract
Background: Periorbital hyperpigmentation is a common worldwide problem, which makes a person appear tired, sad, and aged. A number of factors can cause dark circles around the eyes including excessive pigmentation, thin and translucent lower eyelid skin overlying the orbicularis oculi muscle, and shadowing due to skin laxity and tear trough. Although a number of treatment options are available, autologous fat transplantation is an effective method for the treatment of lower lid dark circles, but irregularities caused by leaving visible lumps of the fat can occur. Mechanical emulsification of harvested fat achieves much more finer fat particles than micro-fat called nano-fat which acts primarily by the plenty the active transplanted stem cells the purpose of this study is to evaluate the effectiveness of the nanofat grafting technique in correcting infraorbital dark circles. Pateints and Methods: Nanofat grafting was performed in 10 female patients for dark lower eyelids. The grafts were injected into intra-dermal and sub-dermal layers using sharp 27G needle and were harvested from different sites according to the ease of accessibility and to improve the patient's body contours. The mean follow-up period was 4.6 months, ranging from 2 to 8 months. All patients were clinically evaluated using standardized serial digital photographs by two plastic surgeons, who were blinded to the type of procedure performed at each of the follow-up visits. Results: In this study, there was significant improvement of the peri-ocular dark halos in 5 cases (50%), moderate improvement was encountered in 2 cases (20%), 2 cases (20%) showed mild improvement and no improvement in one case (10%). As regards patient satisfaction, 8 cases (80%) were satisfied with the final result, while 2 patients (20%) were not satisfied. Post-operative edema and ecchymosis were minimal in 5 cases (50%) and mild in 5 cases (50%). No cases were presented with either post injection infection or lumps and contour irregularities during the follow-up period. Conclusion: In conclusion, nano fat injections for the treatment of infra orbital dark circles is a simple, cost effective procedure. In addition, nanofat grafting technique provided a significant improvement in skin quality. Our results suggest that the stem cell activity of the nanofat grafting technique has great potential as a treatment modality for dark circles as well as for skin rejuvenation in general.
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