ZEINELDIN,, R., MENZES, M., UBEDALLA KHAN, M., SUNDRAM, S. (2025). Invasive Zygomycete Infection of Silicone Augmentation Mammoplasty in an Immunocompetent Patient: Case Report. The Egyptian Journal of Plastic and Reconstructive Surgery, 49(2), 99-101. doi: 10.21608/ejprs.2025.425125
RANIA ZEINELDIN,; MANIK MENZES; MOHAMED UBEDALLA KHAN; SUPRYIA SUNDRAM. "Invasive Zygomycete Infection of Silicone Augmentation Mammoplasty in an Immunocompetent Patient: Case Report". The Egyptian Journal of Plastic and Reconstructive Surgery, 49, 2, 2025, 99-101. doi: 10.21608/ejprs.2025.425125
ZEINELDIN,, R., MENZES, M., UBEDALLA KHAN, M., SUNDRAM, S. (2025). 'Invasive Zygomycete Infection of Silicone Augmentation Mammoplasty in an Immunocompetent Patient: Case Report', The Egyptian Journal of Plastic and Reconstructive Surgery, 49(2), pp. 99-101. doi: 10.21608/ejprs.2025.425125
ZEINELDIN,, R., MENZES, M., UBEDALLA KHAN, M., SUNDRAM, S. Invasive Zygomycete Infection of Silicone Augmentation Mammoplasty in an Immunocompetent Patient: Case Report. The Egyptian Journal of Plastic and Reconstructive Surgery, 2025; 49(2): 99-101. doi: 10.21608/ejprs.2025.425125
Invasive Zygomycete Infection of Silicone Augmentation Mammoplasty in an Immunocompetent Patient: Case Report
1The Department of Pulmonology and Respiratory Diseases, Burjeel Hospital Abu Dhabi, UAE
2The Department of Plastic Surgery, Burjeel Hospital Abu Dhabi, UAE
3The Department of Anaesthesia, Burjeel Hospital Abu Dhabi, UAE Correspondence to:
4The Department of Pulmonology and Respiratory Diseases, Burjeel Hospital Abu Dhabi, UAE
Abstract
Background: Invasive Zygomycete infection of the skin and Subcutaneous tissue is rare but can be life-threatening. Although seen more commonly in immunosuppressed patients such as those with diabetes or malignancy, it is now increasingly being reported in immunocompetent patients. Objective: We report a patient who presented with fever five days post-aesthetic surgery for bilateral breast implants. Summary of a Case: Severe pain and erythema were noted at the wound site of the implant on the right breast initially spreading later to the left breast. Debridement and surgical removal of breast implants were carried out. Zygomycete species were identified in the necrotic tissue. Fungal infection should be suspected in patients not responding to conventional antibiotics. Infection may be iatrogenic and needs a high index of suspicion. Successful treatment is possible only if an early and timely diagnosis is made. Adequate surgical debridement and a prolonged oral systemic antifungal treatment allowed full recovery.
Corcione S., Lupia T., and De Rosa F.G.: Skin and soft tissue Infections after breast surgery. Curr. Opin. Infect Dis., 32 (2): p. 87-94, 2019. 2- Chander J., et al.: Saksenaea erythrospora, an emerging Mucoralean fungus causing severe necrotizing skin and Soft tissue infections: A study from a tertiary care hospital In North India. Infectious Diseases, 49 (3): p. 170-177, 2017. 3- Sanath A.K., et al.: Mucormycosis occurring in an immunocompetent patient: A case report and review of literature. Cesk Patol, 56 (4): p. 223-226, 2020. 4- Reid G., et al.: Mucormycosis. Semin Respir Crit Care Med., 41 (1): p. 99-114, 2020. 5- Riley T.T., et al.: Breaking the Mold: A Review of Mucormycosis and Current Pharmacological Treatment Options. Ann. Pharmacother, 50 (9): p. 747-57, 2016. 6- Panchanatheeswaran K., et al.: Thoracic Mucormycosis in immunocompetent patients. J. Card Surg.,36 (4): p. 1183- 1188, 2021. 7- Baezzat S.R., et al.: Primary breast Mucormycosis, a case report. Iran Red Crescent Med. J., 13 (3): p. 208-9, 2011. 8- Rodríguez J.Y., et al.: Saksenaea erythrospora infection After medical tourism for aesthetic breast augmentation surgery. Int J Infect Dis, 2016. 49: p. 107-10. 9- Lynch Iii, J.P. and Zhanel G.G.: Part 2: Mucormycosis: Focus on therapy. Expert Review of Anti-infective Therapy, 21 (7): p. 737-748, 2023. 10- Ibrahim A.S., et al.: Deferiprone iron chelation as a novel therapy for experimental Mucormycosis. J. Antimicrob Chemother, 58 (5): p. 1070-3, 2006.
Corcione S., Lupia T., and De Rosa F.G.: Skin and soft tissue Infections after breast surgery. Curr. Opin. Infect Dis., 32 (2): p. 87-94, 2019. 2- Chander J., et al.: Saksenaea erythrospora, an emerging Mucoralean fungus causing severe necrotizing skin and soft tissue infections a study from a tertiary care hospital In North India. Infectious Diseases, 49 (3): p. 170-177, 2017. 3- Sanath A.K., et al.: Mucormycosis occurring in an immunocompetent patient: A case report and review of literature. Cesk Patol, 56 (4): p. 223-226, 2020. 4- Reid G., et al.: Mucormycosis. Semin Respir Crit Care Med.., 41 (1): p. 99-114, 2020. 5- Riley T.T., et al.: Breaking the Mold: A Review of Mucormycosis and Current Pharmacological Treatment Options. Ann. Pharmacother, 50 (9): p. 747-57, 2016. 6- Panchanatheeswaran K., et al.: Thoracic Mucormycosis in immunocompetent patients. J. Card Surg.,36 (4): p. 1183- 1188, 2021. 7- Baezzat S.R., et al.: Primary breast Mucormycosis, a case report. Iran Red Crescent Med. J., 13 (3): p. 208-9, 2011. 8- Rodríguez J.Y., et al.: Saksenaea erythrospora infection After medical tourism for aesthetic breast augmentation surgery. Int J Infect Dis, 2016. 49: p. 107-10. 9- Lynch Iii J.P., and Zhanel, G.G.: Part 2: Mucormycosis: Focus on therapy. Expert Review of Anti-infective Therapy, 21 (7): p. 737-748, 2023. 10- Ibrahim A.S., et al.: Deferiprone iron chelation as a novel therapy for experimental Mucormycosis. J. Antimicrob Chemother, 58 (5): p. 1070-3, 2006.
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