Invasive Zygomycete Infection of Silicone Augmentation Mammoplasty in an Immunocompetent Patient: Case Report

Document Type : Case Report

Authors

1 The Department of Pulmonology and Respiratory Diseases, Burjeel Hospital Abu Dhabi, UAE

2 The Department of Plastic Surgery, Burjeel Hospital Abu Dhabi, UAE

3 The Department of Anaesthesia, Burjeel Hospital Abu Dhabi, UAE Correspondence to:

Abstract

Background: Invasive Zygomycete infection of the skin and
Subcutaneous tissue is rare but can be life-threatening. Although
seen more commonly in immunosuppressed patients
such as those with diabetes or malignancy, it is now increasingly
being reported in immunocompetent patients.
Objective: We report a patient who presented with fever
five days post-aesthetic surgery for bilateral breast implants.
Summary of a Case: Severe pain and erythema were noted
at the wound site of the implant on the right breast initially
spreading later to the left breast. Debridement and surgical removal
of breast implants were carried out. Zygomycete species
were identified in the necrotic tissue. Fungal infection should
be suspected in patients not responding to conventional antibiotics.
Infection may be iatrogenic and needs a high index
of suspicion. Successful treatment is possible only if an early
and timely diagnosis is made. Adequate surgical debridement
and a prolonged oral systemic antifungal treatment
allowed full recovery.

Keywords

Main Subjects

References

Corcione S., Lupia T., and De Rosa F.G.: Skin and soft tissue
Infections after breast surgery. Curr. Opin. Infect Dis.,
32 (2): p. 87-94, 2019.
2- Chander J., et al.: Saksenaea erythrospora, an emerging
Mucoralean fungus causing severe necrotizing skin and
Soft tissue infections: A study from a tertiary care hospital
In North India. Infectious Diseases, 49 (3): p. 170-177,
2017.
3- Sanath A.K., et al.: Mucormycosis occurring in an immunocompetent
patient: A case report and review of literature.
Cesk Patol, 56 (4): p. 223-226, 2020.
4- Reid G., et al.: Mucormycosis. Semin Respir Crit Care
Med., 41 (1): p. 99-114, 2020.
5- Riley T.T., et al.: Breaking the Mold: A Review of Mucormycosis
and Current Pharmacological Treatment Options.
Ann. Pharmacother, 50 (9): p. 747-57, 2016.
6- Panchanatheeswaran K., et al.: Thoracic Mucormycosis in
immunocompetent patients. J. Card Surg.,36 (4): p. 1183-
1188, 2021.
7- Baezzat S.R., et al.: Primary breast Mucormycosis, a case
report. Iran Red Crescent Med. J., 13 (3): p. 208-9, 2011.
8- Rodríguez J.Y., et al.: Saksenaea erythrospora infection
After medical tourism for aesthetic breast augmentation surgery.
Int J Infect Dis, 2016. 49: p. 107-10.
9- Lynch Iii, J.P. and Zhanel G.G.: Part 2: Mucormycosis: Focus
on therapy. Expert Review of Anti-infective Therapy,
21 (7): p. 737-748, 2023.
10- Ibrahim A.S., et al.: Deferiprone iron chelation as a novel
therapy for experimental Mucormycosis. J. Antimicrob
Chemother, 58 (5): p. 1070-3, 2006.
Corcione S., Lupia T., and De Rosa F.G.: Skin and soft tissue
Infections after breast surgery. Curr. Opin. Infect Dis.,
32 (2): p. 87-94, 2019.
2- Chander J., et al.: Saksenaea erythrospora, an emerging
Mucoralean fungus causing severe necrotizing skin and
soft tissue infections a study from a tertiary care hospital
In North India. Infectious Diseases, 49 (3): p. 170-177,
2017.
3- Sanath A.K., et al.: Mucormycosis occurring in an immunocompetent
patient: A case report and review of literature.
Cesk Patol, 56 (4): p. 223-226, 2020.
4- Reid G., et al.: Mucormycosis. Semin Respir Crit Care
Med.., 41 (1): p. 99-114, 2020.
5- Riley T.T., et al.: Breaking the Mold: A Review of Mucormycosis
and Current Pharmacological Treatment Options.
Ann. Pharmacother, 50 (9): p. 747-57, 2016.
6- Panchanatheeswaran K., et al.: Thoracic Mucormycosis in
immunocompetent patients. J. Card Surg.,36 (4): p. 1183-
1188, 2021.
7- Baezzat S.R., et al.: Primary breast Mucormycosis, a case
report. Iran Red Crescent Med. J., 13 (3): p. 208-9, 2011.
8- Rodríguez J.Y., et al.: Saksenaea erythrospora infection
After medical tourism for aesthetic breast augmentation surgery.
Int J Infect Dis, 2016. 49: p. 107-10.
9- Lynch Iii J.P., and Zhanel, G.G.: Part 2: Mucormycosis: Focus
on therapy. Expert Review of Anti-infective Therapy,
21 (7): p. 737-748, 2023.
10- Ibrahim A.S., et al.: Deferiprone iron chelation as a novel
therapy for experimental Mucormycosis. J. Antimicrob
Chemother, 58 (5): p. 1070-3, 2006.

Files

Share

How to cite

Statistics