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The Egyptian Journal of Plastic and Reconstructive Surgery
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Volume Volume 49 (2025)
Volume Volume 48 (2024)
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Saad Eldin, M., Mahmoud, A., El Meghawry, K., Mohamed, R., Tallal, R. (2024). Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years. The Egyptian Journal of Plastic and Reconstructive Surgery, 48(4), 245-254. doi: 10.21608/ejprs.2024.385090
Mohamed Osama Saad Eldin; Ahmed Ali Mahmoud; Khaled Mohamed El Meghawry; Reffaat Abd Elsabour Mohamed; Raghda Elsayed Tallal. "Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years". The Egyptian Journal of Plastic and Reconstructive Surgery, 48, 4, 2024, 245-254. doi: 10.21608/ejprs.2024.385090
Saad Eldin, M., Mahmoud, A., El Meghawry, K., Mohamed, R., Tallal, R. (2024). 'Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years', The Egyptian Journal of Plastic and Reconstructive Surgery, 48(4), pp. 245-254. doi: 10.21608/ejprs.2024.385090
Saad Eldin, M., Mahmoud, A., El Meghawry, K., Mohamed, R., Tallal, R. Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years. The Egyptian Journal of Plastic and Reconstructive Surgery, 2024; 48(4): 245-254. doi: 10.21608/ejprs.2024.385090

Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years

Article 2, Volume 48, Issue 4, October 2024, Page 245-254  XML PDF (503.94 K)
Document Type: Research article
DOI: 10.21608/ejprs.2024.385090
View on SCiNiTO View on SCiNiTO
Authors
Mohamed Osama Saad Eldin1; Ahmed Ali Mahmoud1; Khaled Mohamed El Meghawry2; Reffaat Abd Elsabour Mohamed* 1; Raghda Elsayed Tallalorcid 1
1The Departments of Plastic, Burn, Reconstructive & Maxillofacial Surgery, Faculty of Medicine, Ain Shams University
2The Departments Anaesthesia, Intensive Care & Pain Management, Faculty of Medicine, Ain Shams University
Abstract
Abstract
Background: Inhalation injury-based respiratory failure is
the main cause of death in patients with severe burns. In general,
damage from smoke inhalation results in airway edema,
inflammation and, subsequently, cellular debris, mucus, fibrin
clots and polymorphonuclear leukocytes PNL combine to form
casts that lead to ventilation/perfusion mismatch and poor oxygenation.
Objective: This meta-analysis aims to review the Guideline
of Management of Acute Smoke Inhalation Injury and discuss
the different modalities and treatment.
Material and Methods: A comprehensive search of the
literature to identify the Guideline of Management of Acute
Smoke Inhalation Injury and discuss the different modalities
and treatment. via electronic databases including OVID, Science
Direct, Springer, Web of Science and Google Scholar. Initial
search will carried out using keywords: “burns, “ARDS,”
“adult respiratory distress syndrome”, “extracorporeal membrane
oxygenation”, “ECMO,” “inhalation injury”, ”smoke
inhalation injury”, and “heparinized oxygen mask”, ”ECMO”.
Results: All published articles were from 2013 to 2022
limited to human studies of different modalities will be analyzed
and compared regarding the criteria of management.
Conclusion: The care of patients with burn related inhalation
injury remains highly challenging. Key topics include
airway management, nebulized heparin, NAC, chest physiotherapy
and ECMO effect.
Early ambulation, nebulized Heparin in combination with
NAC and albuterol was associated with a reduction in the duration
of mechanical and decrease mortality rate.
Key Words: Acute Smoke Inhalation Injury – Burn Injuries
– Nebulized Heparin – Chest Physiotherapy –
ECMO Effect.
Keywords
Acute Smoke Inhalation Injury; Burn Injuries; Nebulized Heparin; Chest Physiotherapy; ECMO Effect
Main Subjects
Burns
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