Osama, M., Ali Hassan, A., maghwry, K., Tallal, R., abd elsabour mohamed, R. (2024). Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years. The Egyptian Journal of Plastic and Reconstructive Surgery, (), -. doi: 10.21608/ejprs.2024.268581.1336
Mohamed Osama; Ahmed Ali Hassan; khaled maghwry; Raghda El Sayed Tallal; refaat abd elsabour mohamed. "Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years". The Egyptian Journal of Plastic and Reconstructive Surgery, , , 2024, -. doi: 10.21608/ejprs.2024.268581.1336
Osama, M., Ali Hassan, A., maghwry, K., Tallal, R., abd elsabour mohamed, R. (2024). 'Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years', The Egyptian Journal of Plastic and Reconstructive Surgery, (), pp. -. doi: 10.21608/ejprs.2024.268581.1336
Osama, M., Ali Hassan, A., maghwry, K., Tallal, R., abd elsabour mohamed, R. Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years. The Egyptian Journal of Plastic and Reconstructive Surgery, 2024; (): -. doi: 10.21608/ejprs.2024.268581.1336
Guideline of Management of Acute Smoke Inhalation Injury: Systematic Review and Meta-Analysis of Last 10 Years
Articles in Press, Accepted Manuscript, Available Online from 18 February 2024
1plastic surgery department, Ain shams university, Cairo, Egypt
2Faculty of Medicine, Ain Shams University
3Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Ain Shams University
4plastic surgery department Faculty Of Medicine Ain Shams University
5ain shams univeresty egypt
Abstract
ABSTRACT
Background: Inhalation injury-based respiratory failure is the main cause of death in patients with severe burns. In general, damage from smoke inhalation results in airway edema, inflammation and, subsequently, cellular debris, mucus, fibrin clots and polymorphonuclear leukocytes PNL combine to form casts that lead to ventilation/perfusion mismatch and poor oxygenation.
Aim of the Work: This meta-analysis aims to review the Guideline of Management of Acute Smoke Inhalation Injury and discuss the different modalities and treatment.
Materials and Methods: A comprehensive search of the literature to identify the Guideline of Management of Acute Smoke Inhalation Injury and discuss the different modalities and treatment. via electronic databases including OVID, Science Direct, Springer, Web of Science and Google Scholar. Initial search will carried out using keywords :“burns, “ARDS,” “adult respiratory distress syndrome ,” “extracorporeal membrane oxygenation” ,“ECMO,” “inhalation injury,” ,”smoke inhalation injury”, and “heparinized oxygen mask”, ”ECMO”.
Results: All published articles were from 2013 to 2022 limited to human studies of different modalities will be analyzed and compared regarding the criteria of management.
Conclusion: The care of patients with burn related inhalation injury remains highly challenging. Key topics include airway management, nebulized heparin, NAC, chest physiotherapy and ECMO effect. Early ambulation ,nebulized Heparin in combination with NAC and albuterol was associated with a reduction in the duration of mechanical and decrease mortality rate
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