Ibrahim, M., Elsadat, A., Emam, S. (2022). A Trial to Improve the Outcome of Patients with Cleft Palate Repair by Using Human Fibrin Glue: A Study in 20 Cases. The Egyptian Journal of Plastic and Reconstructive Surgery, 46(3), 297-306. doi: 10.21608/ejprs.2022.254752
Mostafa F. Ibrahim; Ahmed M. Elsadat; Seham A. Emam. "A Trial to Improve the Outcome of Patients with Cleft Palate Repair by Using Human Fibrin Glue: A Study in 20 Cases". The Egyptian Journal of Plastic and Reconstructive Surgery, 46, 3, 2022, 297-306. doi: 10.21608/ejprs.2022.254752
Ibrahim, M., Elsadat, A., Emam, S. (2022). 'A Trial to Improve the Outcome of Patients with Cleft Palate Repair by Using Human Fibrin Glue: A Study in 20 Cases', The Egyptian Journal of Plastic and Reconstructive Surgery, 46(3), pp. 297-306. doi: 10.21608/ejprs.2022.254752
Ibrahim, M., Elsadat, A., Emam, S. A Trial to Improve the Outcome of Patients with Cleft Palate Repair by Using Human Fibrin Glue: A Study in 20 Cases. The Egyptian Journal of Plastic and Reconstructive Surgery, 2022; 46(3): 297-306. doi: 10.21608/ejprs.2022.254752
A Trial to Improve the Outcome of Patients with Cleft Palate Repair by Using Human Fibrin Glue: A Study in 20 Cases
1The Department of Plastic Surgery, Faculty of Medicine, Beni-Suef University
2The Department of Pediatric Surgery, Faculty of Medicine, Beni-Suef University
Abstract
Introduction: Cleft palates are among the commonest craniofacial abnormalities. Cleft palate repair is not free of complications. The formation of a fistula is the most common complication of palatoplasty. Aim of Work: To rectify the benefit of using human fibrin glue as a catalyst in primary palatoplasty and its effect on lowering the development of postoperative complications. Methods: Primary palatoplasty was performed for twenty patients by double flap palatoplasty with human fibrin glue as a catalyst in the reform from January 2019 to June 2019. Fibrin glue was prepared from fresh frozen plasma to obtain thrombin and cryoprecipitate to obtain fibrinogen. Then was injected between the two palatal flaps and at the suture line as well. Results: Out of twenty patients, 5 cases (25%) showed post-operative complications. Two cases (10%) were complicated by oronasal palatal fistula one of them (5%) were small (2mm) at the intersection of soft and hard palate without any nasal regurgitation and closed spontaneously within two months of post-operative follow-up. The other one (5%) continued for further surgical repair, and it also had early wound infection. Two cases (10%) were complicated by upper airway obstruction, and one patient (5%) was complicated by hemorrhage. Conclusions: The rate of occurrence of complications was less than in other studies that did the same procedure without the utilization of fibrin glue in the repair. More research with more patients and a more extended period of follow-up is recommended.
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