Shakban, A., Mohamed, W., El Attar, A., Abdel Razek, E. (2025). Photo-Biomodulation Therapy versus Saline Dressing in Wound Healing: A Prospective Comparative Study. The Egyptian Journal of Plastic and Reconstructive Surgery, 49(3), 213-222. doi: 10.21608/ejprs.2025.444132
Ahmed Samy Shakban; Wael Hussein Mohamed; Ahmed Ashraf El Attar; El Sayed Mohamed Abdel Razek. "Photo-Biomodulation Therapy versus Saline Dressing in Wound Healing: A Prospective Comparative Study". The Egyptian Journal of Plastic and Reconstructive Surgery, 49, 3, 2025, 213-222. doi: 10.21608/ejprs.2025.444132
Shakban, A., Mohamed, W., El Attar, A., Abdel Razek, E. (2025). 'Photo-Biomodulation Therapy versus Saline Dressing in Wound Healing: A Prospective Comparative Study', The Egyptian Journal of Plastic and Reconstructive Surgery, 49(3), pp. 213-222. doi: 10.21608/ejprs.2025.444132
Shakban, A., Mohamed, W., El Attar, A., Abdel Razek, E. Photo-Biomodulation Therapy versus Saline Dressing in Wound Healing: A Prospective Comparative Study. The Egyptian Journal of Plastic and Reconstructive Surgery, 2025; 49(3): 213-222. doi: 10.21608/ejprs.2025.444132
Photo-Biomodulation Therapy versus Saline Dressing in Wound Healing: A Prospective Comparative Study
1The Department of Plastic & Reconstructive Surgery, Faculty of Medicine, Tanta University
2The Department of General Surgery, Faculty of Medicine, Tanta University :
Abstract
Background: The process of wound healing is a standard physiological reaction to injuries, often resulting in the restoration of normal function and structure in affected tissues. Objective: This work aimed to assess and compare the efficiency and safety of photo-biomodulation (PBM) therapy versus saline dressing in acute wounds. Patients and Methods: This prospective comparative randomized clinical work had been performed on 40 participants aged from 16 to 40 years old, both genders, with acute wounds. Patients were divided into two equal groups: Group A (PBM side): Treated with diode laser and Group B (control side): Treated with saline dressing. Results: Wound site, infection, size of the lesion at baseline and on 7th day were insignificantly different between both groups. Size of the lesion on the 14th day and duration of complete wound healing were significantly lower in group A than group B (p < 0.05). Photographic wound assessment tool score at 14th day was significantly varied between both groups (p < 0.001). Patient satisfaction and visual analogue scale were significantly varied between both groups (p < 0.001). Complication was insignificantly different between both groups. Semi-quantitative histological scoring system on the 14th day was significantly different between both groups (p < 0.001). Conclusions: PBM wounds which received low level laser therapy exhibited advantages in various aspects, including less time needed for complete healing, reduced wound size, lower pain scores, along with favorable results in edges, skin color surrounding the wound, epithelization, granulation tissue, and overall wound assessment score compared to the control side.
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