The Department of Oral and Maxillofacial Surgery Specialist, Private Practice, Cairo, Egypt
Abstract
Background: Hyaluronic acid has an important role in skin viscoelasticity. Objective: The present study was performed to evaluate The effect of injecting the non-cross-linked hyaluronic acid with growth factors and/or hyper-diluted calcium hydroxyapatite for treating facial skin pigmentations and face rejuvenation, including texture, elasticity, and firmness through collagen induction. Methods: 30 female patients who suffered from dry skin with pigmentations, were included in the study. All patients were randomly divided into three groups; the first group was injected with non-cross-linked hyaluronic acid with growth factors, And the second group was injected with hyper-diluted calcium hydroxyapatite filler, while the third group was injected with a hybrid mixture of non-cross-linked hyaluronic acid with growth factors and hyper-diluted calcium hydroxyapatite filler. Digital pictures were taken before the injection and immediately After the injection for assessment of the clinical results as well as during the follow-up periods (2 weeks, 1 month & 3 months). Results: The third group showed a marked reduction in The amount of skin pigmentation at 2 weeks after injection along with improvement in the skin texture and elasticity, those Changes remained stable up to three months after treatment. Conclusion: The use of a hybrid mixture of non-cross linked hyaluronic acid with growth factors & calcium hydroxyapatite Filler provides a marked reduction in the amount of facial pigmentations and provides a better skin texture than The use of each product alone.
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