Comparative Study between the Combination of Nano Fat Grafting with Fractional Carbon Dioxide Laser, versus Nano Fat Grafting Alone in Treatment of Facial Atrophic Acne Scars

Document Type : Original Article

Authors

1 Plastic and Reconstructive Surgery Faculty of medicine, Assiut University

2 Department of Dermatology, Faculty of Medicine, Assiut University

3 Pathology Department, Faculty of Medicine, Assiut University

4 Plastic Surgery, Faculty of Medicine, Assiut University, Egypt

5 Department of Plastic Surgery, Faculty of Medicine, Assiut University

Abstract

Background: Post Acne scars are challengeable cosmetic problems causing psychological distress. Nano fat has gained a lot of interest in management of facial scars. Fraction carbon dioxide laser is one of the most common modalities used in management of acne scars. This paper aims to evaluate the efficacy of combining nano fat with fractional CO2 laser versus nano fat alone for the treatment of post acne facial scars in a randomized, split-face clinical study.
Methods: This prospective, randomized, split-face study was done on 25 patients, above 16 years old, both sexes were included, suffering from atrophic facial acne scars grade 2 and 3 according to Goodman and Baroon scale. Nano fat grafting was performed on both cheeks and fractional CO2 laser on one cheek in a randomized pattern to all patients.
Results: Patient satisfaction showed no significant difference between both sides. Erythema was significantly higher in nano fat grafting with CO2 laser, than in nano fat grafting alone (P

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The Egyptian Journal of Plastic and Reconstructive Surgery
Volume 49, Issue 4
October 2025
Pages 293-298

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