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The Egyptian Journal of Plastic and Reconstructive Surgery
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Volume Volume 42 (2018)
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Issue Issue 1
Farahat, A., Al Shahat, O., Al Khawaga, I., Ibrahim, M. (2018). Clinical and Histo-Pathological Evaluation of Fat Grafting in Chronic Leg Ulcers. The Egyptian Journal of Plastic and Reconstructive Surgery, 42(1), 145-150. doi: 10.21608/ejprs.2018.215080
Ayman Farahat; Osama Al Shahat; Ismaeil Al Khawaga; Mohamed Ibrahim. "Clinical and Histo-Pathological Evaluation of Fat Grafting in Chronic Leg Ulcers". The Egyptian Journal of Plastic and Reconstructive Surgery, 42, 1, 2018, 145-150. doi: 10.21608/ejprs.2018.215080
Farahat, A., Al Shahat, O., Al Khawaga, I., Ibrahim, M. (2018). 'Clinical and Histo-Pathological Evaluation of Fat Grafting in Chronic Leg Ulcers', The Egyptian Journal of Plastic and Reconstructive Surgery, 42(1), pp. 145-150. doi: 10.21608/ejprs.2018.215080
Farahat, A., Al Shahat, O., Al Khawaga, I., Ibrahim, M. Clinical and Histo-Pathological Evaluation of Fat Grafting in Chronic Leg Ulcers. The Egyptian Journal of Plastic and Reconstructive Surgery, 2018; 42(1): 145-150. doi: 10.21608/ejprs.2018.215080

Clinical and Histo-Pathological Evaluation of Fat Grafting in Chronic Leg Ulcers

Article 22, Volume 42, Issue 1, January 2018, Page 145-150  XML PDF (7.42 MB)
Document Type: Original Article
DOI: 10.21608/ejprs.2018.215080
View on SCiNiTO View on SCiNiTO
Authors
Ayman Farahat* 1; Osama Al Shahat1; Ismaeil Al Khawaga2; Mohamed Ibrahimorcid 3
1The Department of Plastic Surgery, Faculty of Medicine, Al-Azhar University
2The Department of General Surgery , Faculty of Medicine, Al-Azhar University
3The Departments of Plastic Surgery, Faculty of Medicine, Al-Azhar University
Abstract
Background: The application of autologous lipo-transfer
(fat grafting) in reconstructive surgery becomes more popular
now as an evidence for the regenerative effect of fat. In our
study we used the autologous lipo-transfer for treatment of
chronic ulcers at leg.
Methods: Twenty patients with chronic leg ulcers included
in our study, ten of them injected with autologous fat (group < br />A), while the other ten patients were on the usual dressings
for chronic ulcers (group B), the duration of our study was
for six months with patient age in both group range from 15-
50 years with mean age 35.3 years for injected group and
34.1 for the conservative group.
Results: Eight of ten chronic leg ulcers (80 percent) that
injected with autologus fat healed completely within average
of 8 weeks. With only 2 complicated, one complicated by
infection while the other with resorption of fat. Only five
patients at the conservative group healed within three months.
Conclusion: We described in our study a simple technique
to improve wound healing in chronic leg ulcers with a background
of vascular diseases, diabetic or traumatic accidents
where other interventional options to achieve wound healing
have failed.
Keywords
Fat grafting; Chronic leg ulcers
Main Subjects
Lower extremity and foot
References
Gronthos S., Zannettino A.C.W., Hay S.J., Shi S., Graves
S.E., Kortesidis A. and Simmons P.J.: Molecular and
cellular characterisation of highly purified stromal stem
cells derived from human bone marrow. Journal of Cell
Science, 116: 1827-35, 2003.
2- Kaminer M.S. and Omura N.E.: Autologous fat transplantation.
Arch. Dermatol., 137 (6): 812-814, 2001.
3- Christopher E.A., Jeffrey E.J., Steinberg, Schwartz, Ali
A. and Kara C.: Clinical Approach to Wounds: Debridement
and Wound Bed Preparation Including the Use of
Dressings and Wound-Healing Adjuvants. Plastic Reconstructive
Surgery, 117 (Suppl.): 72S, 2006.
4- Coleman S.R.: Structural fat grafting: More than permanent
filler. Plastic and Reconstructive Surgery, 118: 108-120,
2006.
5- Lin K., Matsubara Y., Masuda Y., et al.: Characterization
of adipose tissue-derived cells isolated with the Celution
system. Cytotherapy, 10: 417, 2008.
6- Marino G., Moraci M., Armenia E., et al.: Therapy with
autologous adipose-derived regenerative cells for the care
of chronic ulcer of lower limbs in patients with peripheral
arterial disease. J. Surg. Res., 185: 36-44, 2013.
7- F. Caviggioli, D. Forcellini, V. Vinci, G. Cornegliani, F.
Klinger and M. Klinger: “Employment of needles: A
different technique for fat placement,” Plastic and Reconstructive
Surgery, Vol. 130: pp. 373e–374e, 2012.
8- Cervelli V., Gentile P. and Grimaldi M.: Regenerative
surgery: Use of fat grafting combined with platelet-rich
plasma for chronic lower-extremity ulcers. Aesthetic Plast
Surg., 33: 340-345, 2009.
9- Mohan A. and Singh S.: Journal of wound care, Vol. 26,
No 5 May 2017.
10- Tilman Stasch, Julius Hoehne, Tuan Huynh Randy De
Baerdemaeker, Siegfried Grandel and Christian Herold:
Volume 136, Number 6 Débridement and Autologous
Lipotransfer by the American Society of Plastic Surgeons,
2015.
11- Bartsich S. and Norman Morrison WOUNDS: 24 (3): 51,
Volume 24 - Issue 3 - March 2012.

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