• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
The Egyptian Journal of Plastic and Reconstructive Surgery
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 49 (2025)
Volume Volume 48 (2024)
Volume Volume 47 (2023)
Volume Volume 46 (2022)
Volume Volume 45 (2021)
Volume Volume 44 (2020)
Issue Issue 4
Issue Issue 3
Issue Issue 2
Issue Issue 1
Volume Volume 43 (2019)
Volume Volume 42 (2018)
Amin Saleh, M. (2020). A Novel Technique Using Proline Mesh for Simultaneous Excision and Soft Tissue Suspension in the Management of Craniofacial Neurofibromatosis Type 1. The Egyptian Journal of Plastic and Reconstructive Surgery, 44(2), 229-244. doi: 10.21608/ejprs.2020.112458
Mohamed Amin Saleh. "A Novel Technique Using Proline Mesh for Simultaneous Excision and Soft Tissue Suspension in the Management of Craniofacial Neurofibromatosis Type 1". The Egyptian Journal of Plastic and Reconstructive Surgery, 44, 2, 2020, 229-244. doi: 10.21608/ejprs.2020.112458
Amin Saleh, M. (2020). 'A Novel Technique Using Proline Mesh for Simultaneous Excision and Soft Tissue Suspension in the Management of Craniofacial Neurofibromatosis Type 1', The Egyptian Journal of Plastic and Reconstructive Surgery, 44(2), pp. 229-244. doi: 10.21608/ejprs.2020.112458
Amin Saleh, M. A Novel Technique Using Proline Mesh for Simultaneous Excision and Soft Tissue Suspension in the Management of Craniofacial Neurofibromatosis Type 1. The Egyptian Journal of Plastic and Reconstructive Surgery, 2020; 44(2): 229-244. doi: 10.21608/ejprs.2020.112458

A Novel Technique Using Proline Mesh for Simultaneous Excision and Soft Tissue Suspension in the Management of Craniofacial Neurofibromatosis Type 1

Article 2, Volume 44, Issue 2, April 2020, Page 229-244  XML PDF (67.14 MB)
Document Type: Original Article
DOI: 10.21608/ejprs.2020.112458
View on SCiNiTO View on SCiNiTO
Author
Mohamed Amin Saleh*
The Department of Plastic, Reconstruction, Maxillofacial Surgeries and Burn Management, Faculty of Medicine, Ain Shams University, Cairo, Egypt
Abstract
Neurofibromatosis type 1 (NF-1) is an autosomal dominant
disease that result in vast tumor formation. Craniofacial
Neurofibromatosis is rare condition and it commonly affects
the orbitotemporal midface, nose, upper lip, cheek and neck
with a profound impact on the overall aesthetic outcomes in
these patients. Surgical interventions is the gold standard
treatment of neurofibroma. It is always complex and challenging
due to the variability of the number, site, size, progress
and recurrence are unpredictable. The aim of this study to
present our novel technique using proline mesh for simultaneous
excision and tissue suspension. It is a retrospective
study reviewed 17 patients with craniofacial NF-1. Patients
with intracranial extension and needed neurosurgical intervention
were excluded. Objective and subjective analysis was
done using the Mimics software and the need for additional
surgery “NAS” score scale. Results shown that using the
proline mesh to suspend the tissue hand on hand with NF1
tumor excision is of utmost importance, showing reliable long
term satisfactory aesthetic outcome.
Keywords
Neurofibromatosis type 1; Facial subunits; Tissue suspension; Maxillary and mandibular deformities; Proline mesh; Orbitotemporal region; Hemifacial region; Vectors of pull
Main Subjects
Congenital anomalies; Maxillofacial and cranio-maxillo-facial surgery
References
Jett K. and Friedman J.M.: Clinical and genetic aspects
of neurofibromatosis 1. Genet Med., 12: 1-11, 2010.
2- Todman D.: Warts and the kings of Parthia: An ancient
representation of hereditary neurofibromatosis depicted
in coins. J. Hist. Neurosci., 17 (2): 141-146, 2008.
3- Friedrich R.E., Giese M., Schmelzle R., Mautner V.F. and
Scheuer H.A.: Jaw malformations plus displacement and
numerical aberrations of teeth in neurofibromatosis type
1: A descriptive analysis of 48 patients based on panoramic
radiographs and oral findings. J. Craniomaxillofac. Surg.,
31 (1): 1-9, 2003.
4- Chrcanovic B.R., Gomez R.S. and Freire-Maia B.: Neurofibromatosis
type 1 associated with bilateral central
giant cell granuloma of the mandible. J. Craniomaxillofac.
Surg., 39 (7): 538-543, 2011.
5- Friedrich R.E., Hagel C. and Scheurer H.A.: Orbital
dysplasia and plexiform neurofibroma in NF1. J. Craniomaxillofac.
Surg., 36: S152, 2008.
6- Apaydin A. and Chan T.: Oral manifestations of neurofibromatosis
1: A case report. J. Craniomaxillofac. Surg.,
36: S221, 2008.
7- Koblin I. and Reil B.: Changes of the facial skeleton in
cases of neurofibromatosis. J. Maxillofac. Surg., 3 (1):
23-27, 1975.
8- Krastinova-Lolov D. and Hamza F.: The surgical management
of cranio-orbital neurofibromatosis. Ann. Plast.
Surg., 36 (3): 263-269, 1996.
9- Jackson I.T.: Management of craniofacial neurofibromatosis.
Facial Plast. Surg. Clin. North Am., 9 (1): 59-75,
2001.
10- van der Meulen J.: Orbital neurofibromatosis. Clin. Plast.
Surg., 14 (1): 123-135, 1987.
11- Chou E-K., Chen K-T. and Tansipek B.: Palliative surgical
treatment of the plexiform facialneurofibroma e a case
report. J. Plast. Surg. Assoc. R.O.C., 14: 249-255, 2015.
12- Merker V.L., Bredella M.A., Cai W., et al.: Relationship
between whole-body tumor burden, clinical phenotype,
and quality of life in patients with neurofibromatosis.
Am. J. Med. Genet A., 164A: 1431-1437, 2014.
13- Hirbe A.C. and Gutmann D.H.: Neurofibromatosis type
1: A multidisciplinary approach to care. Lancet Neurol.,
13: 834-843, 2014.
14- Parsons C.M., Canter R.J. and Khatri VP.: Surgical management
of neurofibromatosis. Surg. Oncol. Clin. N. Am.,
18: 175-196, 2009.
15- Marchac D.: Intracranial enlargement of the orbital cavity
and palpebral remodeling for orbitopalpebral neurofibromatosis.
Plast. Reconstr. Surg., 73: 534-543, 1984.
16- Jackson I.T.: Neurofibromatosis of the skull base. Clin.
Plast. Surg., 22: 513-530, 1995.
17- Jackson I.T., Carbonnel A., Potparic Z., et al.: Orbitotemporal
neurofibromatosis: Classification and treatment.
Plast. Reconstr. Surg., 92: 1-11, 1993.
18- Lee V., Ragge N.K. and Collin J.R.: Orbitotemporal
neurofibromatosis. Clinical features and surgical management.
Ophthalmology, 111: 382-388, 2004.
19- Marchac D. and Britto J.A.: Remodelling the upper eyelid
in the management of orbitopalpebral neurofibromatosis.
Br. J. Plast. Surg., 58: 944-956, 2005.
20- Erb M.H., Uzcategui N., See R.F. and Burnstine M.A.:
Orbitotemporal neurofibromatosis: classification and
treatment. Orbit., 26: 223-228, 2007.
21- Singhal D., Chen Y.C., Tsai Y.J., et al.: Craniofacial
neurofibromatosis: Treatment of the midface deformity.
J. Craniomaxillofac. Surg., 42: 595-600, 2014.
22- Fattahi T.T.: An overview of facial aesthetic units. J. Oral
Maxillofac. Surg., 61: 1207-1211, 2003.
23- Burget G.C. and Menick F.J.: The subunit principle in
nasal reconstruction. Plast. Reconstr. Surg., 76: 239-247,
1985.
24- Shuxian Z., Wanhua Z. and Bingheng L.: 3D reconstruction
of the structure of a residual limb for customising the
design of a prosthetic socket. Med. Eng. Phys., 27: 67-
74, 2005.
25- Liu Y., Gong Z., He L., et al.: Individual digital design
and functional reconstruction of large mandibular defect
with computer-aided design computer aided manufacture
technique. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi,
19: 803-806, 2005.
26- Li J., Zhang H., Yin P., et al.: A new measurement technique
of thecharacteristics of nutrient artery canals in tibias
using Materialise's Interactive Medical Image Control
System Software. Biomed Res. Int., 2015: 171672, 2015.
27- Gabbay J.S., Yuan J.T., Andrews B.T., et al.: Fibrous
dysplasia of the zygomaticomaxillary region: Outcomes
of surgical intervention. Plast. Reconstr. Surg., 131: 1329-
1338, 2013.
28- Singhal D., Chen Y.C., Chen Y.R., et al.: Soft tissue
management of orbitotemporal neurofibromatosis. J.
Craniofac. Surg., 24: 269-272, 2013.
29- Hivelin M., Wolkenstein P., Lepage C., et al.: Facial
aesthetic unit remodeling procedure for neurofibromatosis
type 1 hemifacial hypertrophy: report on 33 consecutive
adult patients. Plast Reconstr Surg., 125: 1197-1207,
2010. Surg. Oncol. Clin. N. Am., 18: 175-196, 2009.
30- Hivelin M., Wolkenstein P., Lepage C., et al.: Facial
aesthetic unit remodeling procedure for neurofibromatosis
type 1 hemifacial hypertrophy: Report on 33 consecutive
adult patients. Plast. Reconstr. Surg., 125: 1197-1207,
2010.
31- Nguyen R., Ibrahim C., Friedrich R.E., et al.; Growth
behavior of plexiform neurofibromas after surgery. Genet
Med., 15: 691-697, 2013.
32- Altan-Yaycioglu R. and Hintschich C.: Clinical features
and surgical management of orbitotemporal neurofibromatosis:
A retrospective interventional case series. Orbit.,
29: 232-238, 2010.
33- Nagata S.: A systematic multiple stage surgical approach
for attainment of satisfactory and favourable surgical
results in an extremely severe von Recklinghausen's
disease, elephantiasis neurofibromatosa. J. Plast. Reconstr.
Aesthet. Surg., 59: 662-674, 2006.
34- Bruwer A.J. and Kierland R.R.: Neurofibromatosis and
congenital unilateral pulsating and nonpulsating exophthalmos.
AMA Arch. Ophthalmol., 53: 2-12, 1955.
35- Hunt J.C. and Pugh D.G.: Skeletal lesions in neurofibromatosis.
Radiology, 76: 1-20, 1961.
36- Havlik R.J. and Boaz J.: Cranio-orbital-temporal neurofibromatosis:
Are we treating the whole problem? J. Craniofac.
Surg., 9: 529-535, 1998.
37- Hersh J.H.: Health supervision for children with neurofibromatosis.
Pediatrics, 121: 633-642, 2008.
38- Snyder B.J., Hanieh A., Trott J.A., et al.: Transcranial
correction of orbital neurofibromatosis. Plast. Reconstr.
Surg., 102: 633-642, 1998.
39- Greig A.V., Kirkpatrick N.A., Joshi N., et al.: Giant
hemifacial plexiform neurofibroma arising from trigeminal
ganglion. J. Craniofac. Surg., 20: 833-836, 2009.
40- Chen Y.R., Chen K.T. and Noordhoff M.S.: Facial elephantiasis
neurofibromatosa: Excision and skin graft. Ann.
Plast. Surg., 23: 547-551, 1989.
41- Phillips J.H., Gruss J.S., Wells M.D., et al.: Periosteal
suspension of the lower eyelid and cheek following
subciliary exposure of facial fractures. Plast. Reconstr.
Surg., 88: 145-148, 1991.
42- Gomez-Cia T., Sicilia-Castro D., Infante-Cossio P., et al.:
Second human facial allotransplantation to restore a severe
defect following radical resection of bilateral massive
plexiform neurofibromas. Plast. Reconstr. Surg., 127:
995-996, 2011.
43- Singhal D., Chen Y.C., Seselgyte R., Chen P.K. and Chen
Y.R.: Craniofacial neurofibromatosis and tissue expansion:
Long-term results. J. Plast. Reconstr. Aesthet. Surg., 65
(7): 956-959, 2012.
44- Singhal D., Chen Y.C., Fanzio P.M., Lin C.H., Chuang
D.C., Chen Y.R., et al.: Role of free flaps in the management
of craniofacial neurofibromatosis: Soft tissue coverage
and attempted facial reanimation. J. Oral Maxillofac.
Surg., 70 (12): 2916-2922, 2012.
45- Acartürk T.O., Yigenoglu B. and Pekedis O.: Excision
and “transcutaneous” lift in patients with neurofibromatosis
of the fronto-temporo-orbital and auricular regions. J.
Craniofac. Surg., 20: 771-774, 2009.
46- Xie Y., Li Q., Zheng D., et al.: Correction of hemifacial
atrophy with autologous fat transplantation. Ann. Plast.
Surg., 59: 645-653, 2007.
47- Chaudhry I.A., Morales J., Shamsi F.A., et al.: Orbitofacial
neurofibromatosis: Clinical characteristics and treatment
outcome. Eye (Lond), 26: 583-592, 2012

Statistics
Article View: 270
PDF Download: 731
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.